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Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions / Richard Harris.

Harris, Richard F., (author.).

Available copies

  • 8 of 8 copies available at Evergreen Indiana.

Current holds

0 current holds with 8 total copies.

Location Call Number / Copy Notes Barcode Shelving Location Status Due Date
Benton Co PL - Fowler 610.72 HAR (Text) 34044000915957 Adult Nonfiction Available -
Carnegie PL of Steuben Co - Angola 610.72 HAR (Text) 33118000179684 Adult: New Book Available -
Jennings Co PL - North Vernon 610.72 HAR (Text) 30653001406321 Adult Non-Fiction Available -
Mooresville PL - Mooresville 610.72 HAR (Text) 37323005347482 NONFIC Available -
New Castle-Henry County PL - Main 610.72 HARR (Text) 39231033320272 Ratcliffe-Carnegie Reading Room Available -
Pike Co PL - Winslow Branch 610.72 HARR (Text) 38651833148873 Adult Non-Fiction Available -
West Lafayette PL - West Lafayette 610.72 HAR (Text) 31951004200744 Main Floor - New Arrivals Available -
Zionsville PL - Hussey-Mayfield Memorial Branch 610.724 HARRIS (Text) 33946003230435 New Books . 2nd Floor Available -

Record details

  • ISBN: 9780465097906
  • ISBN: 0465097901
  • Physical Description: vii, 278 pages ; 22 cm
  • Publisher: New York : Basic Books, [2017]

Content descriptions

Bibliography, etc. Note: Includes bibliographical references (pages 239-264) and index.
Formatted Contents Note: Begley's bombshell -- It's hard even on the good days -- A bucket of cold water -- Misled by mice -- Trusting the untrustworthy -- Jumping to conclusions -- Show your work -- A broken culture -- The challenge of precision medicine -- Inventing a discipline.
Summary, etc.: "Biomedical science--the research that underlies our treatments and cures--is in deep crisis. Every year, American taxpayers spend more than $30 billion funding it. About half of that work, by some estimates, is wrong. As award-winning science journalist Richard Harris reveals in Rigor Mortis, this is not simply the result of trial and error, which is an essential part of the scientific process. The economic imperative for researchers to get and keep jobs and funding encourages dubious behavior, from poor experimental design to sloppy statistics and shoddy analysis. Add to that a bunch of mislabeled cell lines and mishandled ingredients, and what seems like a potential cure becomes an unreliable mess. Some 900 breast-cancer studies were conducted with cells that weren't breast-cancer cells at all, new "treatments" for ALS developed in rodent models failed when retested properly in mice, and only 1.2 percent of early papers in genomics stand the test of time. These problems aren't the exception. They are commonplace. This crisis of reproducibility--when studies done in one lab fail when another tries to reproduce their results--isn't just holding back scientific progress--it's a devastating blow for patients everywhere who are hoping that medical science will give them longer, healthier lives. Rigor Mortis explores these urgent issues through vivid anecdotes, personal stories, and interviews with the nation's top biomedical researchers, some of whom are now struggling to set things right. An unsparing investigation that lays bare the dysfunctions in our research system, this book represents the first step toward fixing it."--Jacket.
Subject: Medicine > Research > Methodology.
Medical ethics.
MEDICAL > Research.
MEDICAL > Ethics.
SCIENCE > Research & Methodology.
Biomedical Research > methods.
Ethics, Medical.
United States.

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